Table 2

Efficacy as percentage of GABA EC₁₀ response

Ionophore composition	Chlordiazepoxide^2-a	DMCM^2-a^,^2-b	Phenobarbital^2-a^,^2-c
	%
α1β2γ2	397 ± 23	69 ± 5	1129 ± 87
α1^Mβ2γ2	594 ± 16	ND^2-d	823 ± 113^2-c
α1β2^Mγ2	196 ± 9	ND	935 ± 78^2-c
α1β2γ2^M	282 ± 10	60 ± 4	1113 ± 236^2-c

↵2-a Mean ± SEM (n = 3).
↵2-b The mutant channel efficacy was not significantly different from wild-type channel as determined by at test (p = 0.23).
↵2-c The mutant channels’ efficacies were not significantly different from wild-type channels as determined by one-way ANOVA (p = 0.42).
↵2-d ND, not determined.