Summary of kinetic results
| Drug | τ = on | τ = off | Amplitude | n |
|---|---|---|---|---|
| sec | pA | |||
| ME | 0.71 ± 0.05 | 1.42 ± 0.08 | 360 ± 30 | 44 |
| DAMGO | 0.73 ± 0.12 | 0.92 ± 0.102-a | 432 ± 892-a | 9 |
| (0.66 ± 0.11) | (1.45 ± 0.16) | (509 ± 94) | ||
| DSLET | 0.77 ± 0.09 | 0.72 ± 0.102-a | 261 ± 392-a | 12 |
| (0.66 ± 0.24) | (1.46 ± 0.16) | (380 ± 44) | ||
| Etorphine | 0.73 ± 0.09 | >202-a | 225 ± 412-a | 12 |
| (0.86 ± 0.16) | (298 ± 51) | |||
| UK14304 | 0.31 ± 0.032-a | 0.93 ± 0.092-a | 290 ± 49 | 11 |
| (0.75 ± 0.11) | (1.37 ± 0.11) | (285 ± 42) | ||
All experiments were paired with the response to ME (100 μm). The numbers in parentheses indicate the mean values for ME (100 μm) in that group of cells. Statistical analysis was done with a paired t test.
↵2-a Difference in response between the test drug and ME (p < 0.05).