Table 3

Reduction in TQ by NQO1-transfected CHO sonicates

Cell lineCHO-glyACHO-815CHO-812
nmol of DCPIP/min/mg of protein
NQO1 activityN.D.3-a 981300
TQ reduced3-b 0.3 ± 0.275.0 ± 0.5411.0 ± 0.03

Reaction conditions are described in the text.

    • ↵3-a Not detectable above control (minus sonicate) levels. Limit of detection <5 nmol of DCPIP/min/mg of protein.

    • ↵3-b nmol of TQ reduced in 30 min.

    • Values are mean ± standard deviations from three separate determinations.