Table 2

Correlations between UV sensitivity, BCNU cytotoxicity and MGMT or ERCC2 expression in 14 human tumor cell lines

Regression formularp
UV-BCNU y = 0.15x + 5.22-a 0.8580.0001
UV-ERCC2 (protein level) y = 28.7x + 9.72-a 0.8740.0001
UV-MGMT (protein level) y = −4.3x + 14.92-a 0.1530.6017
UV-MGMT (activity) y = −1.0x + 14.42-a 0.1030.7255
BCNU-ERCC2 (protein level) y = 148.7x + 36.52-b 0.7860.0009
BCNU-MGMT (protein level) y = 21.8x + 51.92-b 0.1390.6348
BCNU-MGMT (activity) y = 7.4x + 53.12-b 0.1310.6515
  • 2-a y represents UV sensitivity and x represents either BCNU cytotoxicity, ERCC2 protein level, MGMT protein level, or MGMT activity.

  • 2-b y represents BCNU cytotoxicity andx represents either ERCC2 protein level, MGMT protein level, or MGMT activity.