Table 4

Rat nucleus accumbens: displacement of [125I]AC512

AntagonistpKiAgonistpKi highpKi lowH
%
AC51210.47  ± 0.09rAMYLIN10.17  ± 0.187.8  ± 0.2446
(n = 6)(n = 6)
AC669.4  ± 0.08Rat CAL7.5  ± 0.305.1  ± 0.3030
(n = 5)(n = 5)
AC4139.86  ± 0.28hCAL7.3  ± 0.194.95  ± 0.0942
(n = 5)(n = 5)
hCGRP8–37 8.31  ± 0.37rCGRP9.21  ± 0.207.06  ± 0.0851
(n = 5)(n = 5)
Eel CAL10.9  ± 0.09100
(n = 4)