Compound | EC50 | CC50 | |
---|---|---|---|
Wild-type NL4-3 | AR177r NL4-3 | ||
μg/ml | |||
AR177 | 0.6 | >125 | >125 |
DS (M r 5000) | 0.7 | 23.8 | >125 |
Heparin | 0.2 | 3.9 | >125 |
ISI5320 | 0.2 | >10 | >10 |
AMD3100 | 0.003 | 0.004 | >125 |
EC50 based on the inhibition of HIV-induced cytopathicity in MT-4 cells, as determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium method. CC50 based on the viability of MT-4 cells, as determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium method.