Table 2

Statistics for CoMFA models

Model	Field type^2-a	q² ^2-b	N^2-c	r² ^2-d	s^2-e	F^2-f	ste^2-g	lip^h
1	ste	0.57	3	0.953	0.147	263	100
2	lip	0.34	5	0.964	0.132	198		100
3	ste and lip	0.47	4	0.967	0.124	282	41.9	58.1

↵2-a Molecular field(s) used in CoMFA: ste, steric field; ele, electrostatic field; lip, lipophilic field.
↵2-b Cross-validation correlation coefficient.
↵2-c Number of components used in final PLS analyses (see text).
↵2-d Correlation coefficient of the final PLS analysis.
↵2-e Standard error of estimate, measure of the unexplained uncertainty.
↵2-f F ratio: the higher the F ratio, the better the PLS analysis.
↵2-g Relative contribution of the steric (ste) and lipophilic (lip) fields in the final PLS analysis.