Table 2

Cytotoxicity of NSC 314622 in human leukemia CEM and camptothecin-resistant CEM/C2 cells

NSC 314622 concentrationExposureGrowth fraction2-a
CEMCEM/C2
6 μm  1 hr0.230.53Exp #1
10 μm  1 hr0.030.29Exp #2
0.1 μm 48 hr0.290.50Exp #2
0.1 μm 48 hr0.330.60Exp #3
  • 2-a Cells were counted 48 hr after the beginning of drug treatment.