Table 2

Perfusion data for study 2

Perfusion conditionsNumber of tubules studiedMean luminal Hg2+ concentrationContent of Hg2+ in TCA-soluble tubule fractionContent of Hg2+ in TCA-insoluble tubule fractionLeak
Present in luminal fluidPresent in bathing fluid
μm fmol/mm fmol/mm nl/min
None20 μm Hg2+ 30.24  ± 0.201.00  ± 0.516845  ± 17679.03  ± 5.10
None20 μm Hg2+ + 200 μmDMPS30.46  ± 0.123.32  ± 3.9830.7  ± 16.12-a 0.33  ± 0.062-a

Values represent the mean ± standard error obtained from isolated perfused S2 segments of proximal tubules. Refer to Materials and Methods for details of the experimental design.

    • 2-a Significantly different (p < 0.05) from all of the other corresponding means.