Potencies of HPLC-purified adenine nucleoside di- and triphosphates in human P2Y1-1321N1 cells
| Nucleotide | EC50 |
|---|---|
| nm | |
| 2MeSADP | 2 (0.5–6) |
| ADP | 10 (4–25) |
| 2MeSATP | 116 (18–719) |
| ATP | 304 (191–483) |
Concentration-effect curves were generated for elevation of intracellular Ca2+ concentrations, as described in the legend to Fig. 2. EC50 values were calculated by nonlinear regression (GraphPAD Prism; GraphPAD Software). Values in parentheses are 95% confidence intervals.