Binding affinities of the test compounds for single-stranded DNA in ETN buffer (0.1 m, pH 7.0, 25°)
| Compound | Ki (×10−4)3-a |
|---|---|
| m −1 | |
| 9-IHA | 37.9 ± 3.0 |
| Aza-9-IHA | 12.2 ± 0.9 |
| 1-IHA | 5.9 ± 0.5 |
| Bisantrene | 101.2 ± 7.9 |
The values of the exclusion parameter n were always close to 2 bases.
↵3-a Intrinsic binding constant.