Anti-HIV-1 activity, inhibition of 12G5 mAb binding and inhibition of [Ca++]i flux of AMD3100 and its different transition metal complexes
↵3-a EC50 as measured by the MTT assay.
↵3-b IC50: 50% inhibitory concentration, or concentration of the compound required to inhibit by 50% the binding of 12G5 mAb to CXCR4+ SUP-T1 cells.
↵3-c IC50 [Ca2+]i by SDF-1α in SUP-T1 cells.