Table 3

Comparison of KATP channel modulators in different preparations

AbscissaOrdinaterSloped
Rat cardiac membranesSUR2A0.980.98  ± 0.08−0.28  ± 0.07
Rat aortic stripsSUR2B0.950.96  ± 0.12−0.27  ± 0.13
SUR2BSUR2A1.000.96  ± 0.04−0.55  ± 0.043-a

Linear correlation analysis of the pKi values listed in Table 2 gave correlation coefficients (r), slopes (s), and mean distance (d) from line of identity as listed below. s = 1 means that Ki values on the two axes are proportional to one another and 10d gives factor by which, in mean, Ki values on ordinate differ from those on abscissa.

  • 3-a Correlation analysis taking into account openers only.