Receptor | T1/2of Internalization |
---|---|
min | |
rLHR-wt | 108 ± 7 |
rLHR-L613,614,615,616A | 42 ± 41-150 |
rLHR-L613,614A | 16 ± 21-150 |
rLHR-L615,616A | 76 ± 51-150 |
rLHR-L613A | 33 ± 141-150 |
rLHR-L614A | 49 ± 81-150 |
Cells were transiently transfected with the indicated constructs. TheT1/2 values for internalization of the125I-hCG-rLHR complexes were measured as described inMaterials and Methods.
Each value represents the mean ± S.E.M. of three to six independent transfections.
↵1-150 p < .05 compared with rLHR-wt.