Cell Line | [3H]CycloSal-AZTMP | |||
---|---|---|---|---|
AZT + Prodrug (fr 2-3)3-a | AZTMP (fr 9-10)3-a | AZTDP (fr 14-15)3-a | AZTTP (fr 22-23)3-a | |
pmol/109cells | ||||
CEM | 39 | 5,5475 | 236 | 425 |
MT-4 | 64 | 2,002 | 267 | 385 |
MOLT 4/C8 | 111 | 7,854 | 357 | 755 |
DAUDI | 58 | 11,572 | 781 | 1,920 |
PBL (resting) | 5.8 | 2.6 | 0.33 | 0.5 |
PBL (activated) | 17 | 843 | 22 | 33 |
M/M | 23 | 1,044 | 28 | 29 |
Values are the mean of two to four independent experiments.
↵3-a The values within parentheses represent the elution times (min) (or fraction numbers) of the metabolites. Each fraction contains 1 ml, collected in 1 min.