Metabolites of [3H]AZT in PBL cells after 24 h of incubation
| Cell Line | [3H]AZT | |||
|---|---|---|---|---|
| AZT (fr 2-3)4-a | AZTMP (fr 9-10-11)4-a | AZTDP (fr 15-16-17)4-a | AZTTP (fr 24-25-26)4-a | |
| pmol/109 cells | ||||
| PBL | 3.0 | 3.6 | 0.53 | 0.57 |
| PBL (activated) | 30 | 2,202 | 38 | 44 |
Values are the mean of two independent experiments.
↵4-a The values within parentheses represent the elution times (min) (or fraction numbers) of the metabolites. Each fraction contains 1 ml, collected in 1 min.