Concentration of 5′-monophosphates of nucleoside analogs that inhibits cytosolic 3′-to-5′ exonuclease by 50%
| ID50 | ||||
|---|---|---|---|---|
| β-d-d4TMP | β-d-FddCMP | β-l-Fd4CMP | β-l-OddCMP | β-l-FddCMP |
| μM | ||||
| 86 ± 15 | 84 ± 10 | 38 ± 9 | 400 ± 59 | 320 ± 50 |
Values and S.D. are from one experiment repeated at least three times with close results.