Table 1

Kinetic parameters for 3H-LTD4 and3H-LTC4

3H-LTD43H-LTC4
k on1 2.7 × 106  ± 281.5 × 107  ± 96
K d1 0.063 K d1 0.053
k off1 1.7 × 10−4  ± 397.8 × 10−4  ± 33
B max1 0.0073  ± 170.0095  ± 42
k on2 1.8 × 105  ± 853.3 × 105  ± 51
K d2 21.7 K d2 83
k off2 4 × 10−3  ± 452.7 × 10−2  ± 35
B max2 0.074  ± 875.5  ± 26

kon values are expressed in M−1 · s−1. koff values are expressed as s−1. Kd values are the ratio ofkoff to kon and are expressed in nM. Bmax values are expressed as pmol/mg protein. Parameters are expressed as mean ± % CV.