Treatment | Binding of [3H]ALDO |
---|---|
cpm/incubation | |
Control | 8180 ± 435 |
10 mM Pyridoxal 5′-phosphate + 60 mM l-Lys | 7295 ± 785 |
10 mM Pyridoxal 5′-phosphate | 1488 ± 381a |
Preincubation with 20 nM ALDO | 5988 ± 880b 4-c |
Preincubation with 300 nM 11-OP | 1377 ± 279a |
Preincubation with 1 μM 6-OP | 1607 ± 556a |
Different from control ata P < .001 andb P < .05.
↵4-c Different from treatment of unoccupied MR atP < .001.