Burst Duration | |||
---|---|---|---|
0.5 μM GABA | +100 μM PB | 100 μM PB | |
Time constant | |||
τ1 | 0.4 ± 0.3 | 0.5 ± 0.2 | 1.0 ± 0.6 |
τ2 | 3.4 ± 0.8 | ||
τ3 | 22 ± 4 | 22 ± 10 | 19 ± 8 |
τ4 | 87 ± 19 | 73 ± 20 | |
Area % | |||
A1 | 28 ± 9 | 8 ± 4 | 14 ± 4 |
A2 | 36 ± 6 | ||
A3 | 37 ± 12 | 10 ± 5 | 44 ± 13 |
A4 | 82 ± 7 | 42 ± 15 |
Time constants (τi, ms) and the relative areas (Ai) of burst duration for channels activated by 0.5 μM GABA alone and later 0.5 μM GABA plus 100 μM pentobarbital (n = 4) or activated by 100 μM pentobarbital alone (n = 6). Data were fitted with sums of three or four exponential functions (means ± 1 S.E.).
PB, pentobarbital.