Table 2

Reversal of vanadium(+4)-evoked inhibition of acid phosphatase at pH 7.2 by various chelators

LigandConcentration for Half-Maximally Reversing Vanadium(+4)-Evoked Inhibition of Acid PhosphataseFormation Constant Keff/pH 7.2
mM [103M−1]
EDTA0.024  ± 0.00341.4
Picolinate0.17  ± 0.0085.8
Maltolate0.48  ± 0.032.07
l-Glu(γ)HXM6.0  ± 0.40.165
l-Asp(β)HXM5.4  ± 0.30.184
l-Ile(α)HXM21  ± 30.047
GSH>100<0.01
Citrate>100<0.01
l-Gln>100<0.01
l-Asn>100<0.01
l-Glu>100<100