Table 2

Impact of CYP2A6 genotype on indicies of smoking

Group 1Group 2Group 3
Genotype CYP2A6*2/2,N = 1 CYP2A6*1/*1, N = 277 CYP2A6*1/*1 plus duplication, N = 5
CYP2A6*1/2, N = 6
CYP2A6*1/*4, N = 7
GenderF = 8/M = 6F = 143/M = 144F = 4/M = 1
CO (ppm)14 ± 2 20 ± 0.62-a 23 ± 42-a
Cotinine plasma levels (ng/ml)217 ± 762-b 265 ± 92-b 378 ± 76 

  • F, female; M, male.

  • ↵2-a  Significantly different from group 1 (P < .05).

  • ↵2-b  Significantly different from group 3 (P < .05).