Cell Line | Agonist | GTPγS Binding log EC50 | Basal | Maximum | Stimulation |
---|---|---|---|---|---|
M | fmol/μg protein | -fold | |||
CHOA1L | CPA | −8.06 ± 0.36 (3) | 0.004 ± 0.001 | 0.009 ± 0.001 | 2.3 |
NECA | −7.34 ± 0.17 (3) | 0.005 ± 0.001 | 0.009 ± 0.001 | 1.8 | |
R-PIA | −7.83 ± 0.23 (3) | 0.005 ± 0.001 | 0.012 ± 0.002 | 2.4 | |
CHOA1H | CPA | −8.22 ± 0.36 (3) | 0.049 ± 0.009 | 0.197 ± 0.058 | 4.0 |
NECA | −7.87 ± 0.08 (3) | 0.042 ± 0.011 | 0.178 ± 0.025 | 4.2 | |
R-PIA | −7.66 ± 0.51 (4) | 0.067 ± 0.019 | 0.277 ± 0.047 | 4.1 |
Values represent means ± S.E.M. obtained from three to four separate experiments (actual number given in parentheses).