A1 agonist concentration-response parameters for A1receptor-stimulated [3H] inositol phosphate accumulation in high and low expressing CHO-K1 cells transfected with the human adenosine A1 receptor
| Cell Line | Agonist | Control log EC50 | Stimulation (Over Basal) |
|---|---|---|---|
| M | -fold | ||
| CHOA1L | CPA | −7.39 ± 0.17 (6) | 1.68 ± 0.12 (6) |
| NECA | −6.90 ± 0.19 (7) | 1.57 ± 0.10 (7) | |
| R-PIA | −6.59 ± 0.14 (6) | 1.59 ± 0.08 (6) | |
| CHOA1H | CPA | −6.86 ± 0.06 (6) | 4.67 ± 0.25 (6) |
| NECA | −6.03 ± 0.08 (11) | 6.75 ± 0.74 (11) | |
| R-PIA | −6.63 ± 0.17 (7) | 5.68 ± 0.49 (7) |
Values represent means ± S.E.M. The number of experiments is given in parentheses.