Sensitivity of HIV-1 RT to the inhibitory effects of the dendrimers and reference compounds
| Compound | IC504-a μg/ml |
|---|---|
| BRI2923 | 0.2 ± 0.1 |
| BRI6195 | 17.1 ± 1.2 |
| DS | 24.5 ± 8.6 |
| R86183 | 0.04 ± 0.03 |
↵4-a IC50 or concentration required to inhibit the HIV-1 RT activity using poly(C) · oligo(dG) as template/primer by 50%.