Relative potencies of calcitonin receptor agonists in transient wild-type and stably expressing HEK 293 wild-type cells
| Agonist | Stable2-a HEK 293 | Transient wild-type |
|---|---|---|
| Amylin | 8.0 ± 0.17 | 7.35 ± 0.2 |
| Rat CAL | 7.96 ± 0.21 | 7.43 ± 0.18 |
| Human CAL | 8.14 ± 0.2 | 7.45 ± 0.18 |
| Porc CAL | 8.29 ± 0.22 | 7.82 ± 0.2 |
| Eel CAL | 8.7 ± 0.24 | 8.38 ± 0.2 |
| Salmon CAL | 8.4 ± 0.17 | 8.07 ± 0.15 |
| Rat CGRP | 6.96 ± 0.15 | 6.92 ± 0.22 |
| Chicken CGRP | 7.92 ± 0.26 | 7.52 ± 0.2 |
Estimates are the mean of three separate transient transfections. pEC50 values are given with S.E.M.
↵2-a Stable HEK 293 cell line containing 30.05 ± 3 pmol/mg of protein hCTR2.