Table 3

The values of rate constants used in the kinetic scheme are presented below

Rates (s−1)ControlPropofolControl/Propofol
kon 1.0 × 106 M−1 1.0 × 106 M−1 1.00
koff 103561.85
β600060001.00
α4004001.00
Df 300016201.85
Rf 2001201.70
Rs 0.0270.0271.00
Ds 26141.85
k−G 0.10.11.00
K−B 0.90.91.00