Relationship between hCNT1 expression and cytotoxic effect of 5′-DFUR
| 5′-DFUR IC50 | ||
|---|---|---|
| − Dipyridamole | +Dipyridamole | |
| WT | 648 ± 66 | 4882 ± 489 |
| PC | 509 ± 32 | 3934 ± 183 |
| HC1 | 207 ± 10 | 309 ± 15 |
Data obtained in the absence of dipyridamole are derived from the cytotoxicity assay shown in Fig.7. IC50 values for 5′-DFUR cytotoxicity assay in the presence of dipyridamole are a summary of data not shown.