(S)-Warfarin | Diclofenac | Lauric Acid | |||||||
---|---|---|---|---|---|---|---|---|---|
Km | Vmax | Vmax/Km | Km | Vmax | Vmax/Km | Km | Vmax | Vmax/Km | |
μM | nmol of product/nmol of P450/min | ml/nmol of P450/min | μM | nmol of product/nmol of P450/min | ml/nmol of P450/min | μM | nmol of product/nmol of P450/min | ml/nmol of P450/min | |
CYP2C9*1 | 5.6 | 0.14 | 0.025 | 4.8 | 29 | 6.04 | 34 | 4.3 | 0.127 |
CYP2C9*3 | 28 | 0.02 | 0.001 | 17 | 13 | 0.76 | 125 | 0.8 | 0.006 |
CYP2C9*5 | 67 | 0.14 | 0.002 | 22 | 25 | 1.14 | 96 | 1.1 | 0.012 |