Table 1
The effects of forskolin on secretory spike parameters
| Imax | t1/2 | Q | m | tPa | n cells | n spike s | |
|---|---|---|---|---|---|---|---|
| pA | ms | pC | nA/s | ms | |||
| Control | 72.6 ± 2.9 | 16.0 ± 0.5 | 1.4 ± 0.06 | 24.2 ± 1.1 | 18.2 ± 1.0 | 12 | 778 |
| Forskolin 100 nM | 64.3 ± 4.6 | 32.9 ± 1.5 | 2.1 ± 0.13 | 17.5 ± 1.6 | 26.1 ± 1.9 | 7 | 308 |
Cells treated with 100 nM forskolin are compared with their own control group (see results). Secretion is elicited by 5 s application of 5 mM BaCl2. All values obtained from forskolin-treated cells are statistically different (p < 0.001) from controls (Mann-Whitney and Kolmogorov-Smirnova tests).
