Antagonist potency of several compounds against the response of 5-HT and (±)-DOI ([3H]IP formation) in CHOFA4 cells expressing human 5-HT2A receptors
| pA2 | ||
|---|---|---|
| 5-HT | (±)-DOI | |
| MDL 100,907 | 8.73 ± 0.46 | 9.34 ± 0.06 |
| Ketanserin | 8.45 ± 0.25 | 9.16 ± 0.30 |
| SB242084 | 7.17 ± 0.33 | 7.47 ± 0.15 |
| Mesulergine | 7.27 ± 0.30 | 7.14 ± 0.30 |
Values represent mean ± S.E.M. of at least three independent experiments performed with triplicate points.