Table 1

IC50 values for t-RESV-induced vasorelaxation in endothelium-containing rat aortic rings precontracted with PE (1 μM) or extracellular high KCl concentration (60 mM) in the absence and presence of atropine (10 μM) or yohimbine (1 μM). Each value represents the mean ± S.E.M. from five experiments

ProtocolsPEKCl
μM
t-RESV3.12  ± 0.269.60  ± 0.87
Atropine + t-RESV2.94  ± 0.239.33  ± 0.76
Yohimbine + t-RESV3.05  ± 0.218.97  ± 0.88