Frequency of CYP1B1 genotypes in Ethiopian population listed in decreasing order of frequency
| Genotype | Trivial Name | No. of subjects | |
|---|---|---|---|
| Observed | Predicted (Hardy-Weinberg) | ||
| CYP1B1*2/*3 | m1 +m2/m3 | 44 (29.3%) | 43 |
| CYP1B1*3/*3 | m3/m3 | 21 (14.0%) | 23 |
| CYP1B1*2/*2 | m1 +m2/m1 + m2 | 19 (12.7%) | 20 |
| CYP1B1*1/*2 | wt/m1 +m2 | 10 (6.7%) | 9.0 |
| CYP1B1*1/*3 | wt/m3 | 10 (6.7%) | 10 |
| CYP1B1*3/*7 | m3/m1 + m2 + m3 + m5 | 9 (6.0%) | 8.0 |
| CYP1B1*2/*6 | m1 + m2/m1 + m2 + m3 | 8 (5.3%) | 7.0 |
| CYP1B1*3/*6 | m3/m1 + m2 + m3 | 8 (5.3%) | 7.4 |
| CYP1B1*2/*7 | m1 + m2/m1 + m2 + m3 + m5 | 7 (4.7%) | 7.7 |
| CYP1B1*1/*7 | wt/m1 + m2 + m3 + m5 | 3 (2.0%) | 1.7 |
| CYP1B1*3/*4 | m3/m4 | 3 (2.0%) | 2.3 |
| CYP1B1*2/*4 | m1 +m2/m4 | 2 (1.3%) | 2.2 |
| CYP1B1*3/*5 | m3/m1 +m3 | 1 (0.7%) | 0.7 |
| CYP1B1*6/*7 | m1 + m2 + m3/m1 + m2 + m3 +m5 | 1 (0.7%) | 1.3 |
| CYP1B1*6/*6 | m1 + m2 + m3/m1 + m2 +m3 | 1 (0.7%) | 0.6 |
| CYP1B1*4/*7 | m4/m1 + m2 + m3 +m5 | 1 (0.7%) | 0.4 |
| CYP1B1*2/*5 | m1 + m2/m1 +m3 | 1 (0.7%) | 0.6 |
| CYP1B1*1/*1 | wt/wt | 1 (0.7%) | 1.0 |
Eighteen different combinations of CYP1B1 alleles were found among 150 Ethiopians. The observed genotype distribution pattern was consistent with the expected frequencies according to Hardy-Weinberg equilibrium.