MALDI-MS | Dexniguldipine Incorporationa) | Tryptic P-gp Peptide | Lysine Residues | Molecular Mass (Theoretical) |
---|---|---|---|---|
m/z | aa | Da | ||
7416 | – | 147–210 | 3 | 7417 |
2-213 | 443–502 | 1 | 7420 | |
2-213 | 468–527 | 4 | 7418 | |
5734 | – | 620–670 | 3 | 5735 |
2-213 | 1015–1061 | 1 | 5734 | |
5230 | – | 620–666 | 3 | 5235 |
2-213 | 618–659 | 3 | 5228 |
Photochemical incorporation of dexniguldipine leads to a mass increment of 577 amu. Molecular mass was calculated from the amino acid sequence.
↵2-213 , incorporation of dexniguldipine; –, no incorporation.