Statistical analysis of the conservation pattern in a continuous stretch of residues from 3.33 to 3.48 in TMH 3 of all GPCR sequences denoted as (Rhod)opsin and Amine in GPCRDB.
| Position | (Rhod)opsin | Amine |
|---|---|---|
| % | ||
| 3.33 | Thr 51.4 | Val 64.6 |
| 3.34 | Leu 65.7 | Leu 51.0 |
| 3.35 | Gly 50.0 | Cys 53.1 |
| 3.36 | Gly 98.8 | Cys 56.9 |
| 3.37 | Glu 34.3 | Thr 85.1 |
| 3.38 | Ile 33.1 | Ala 82.6 |
| 3.39 | Ala 41.2 | Ser 100.0 |
| 3.40 | Leu 66.9 | Ile 85.8 |
| 3.41 | Trp 85.3 | Leu 43.4 |
| 3.42 | Ser 77.1 | Asn 42.4 |
| 3.43 | Leu 80.4 | Leu 89.9 |
| 3.44 | Val 40.8 | Cys 72.6 |
| 3.45 | Val 55.5 | Ala 41.7 |
| 3.46 | Leu 54.3 | Ile 92.1 |
| 3.47 | Ala 75.9 | Ser 65.3 |
| 3.48 | Ile 33.5 | Leu 42.0 |
The position in the helix, the amino acid most often present at this position, and the population of this amino acid in the family are shown.