Regional [3H]cytisine binding (femtomoles per milligram ± S.E.M.) in 14 inbred mouse strains
| CX | SE | HP | ST | HT | TH | MB | HB | |
|---|---|---|---|---|---|---|---|---|
| A | 88.80 ± 5.84 | 43.40 ± 7.64 | 66.70 ± 4.74 | 112.15 ± 3.01 | 65.33 ± 5.03 | 193.72 ± 15.51 | 113.03 ± 15.31 | 79.33 ± 3.23 |
| BALB | 79.67 ± 5.97 | 44.85 ± 10.36 | 61.52 ± 4.34 | 93.12 ± 5.15 | 56.88 ± 4.33 | 205.73 ± 14.59 | 110.13 ± 5.92 | 91.57 ± 4.22 |
| BUB | 63.74 ± 3.67 | 38.89 ± 8.71 | 53.23 ± 3.00 | 93.77 ± 4.08 | 55.14 ± 4.36 | 162.13 ± 9.96 | 99.23 ± 11.64 | 81.67 ± 3.31 |
| CBA | 75.37 ± 6.35 | 37.63 ± 7.97 | 45.07 ± 4.63 | 95.10 ± 3.97 | 43.91 ± 5.52 | 163.10 ± 5.10 | 100.11 ± 10.45 | 63.20 ± 4.08 |
| C3H/2 | 79.25 ± 3.66 | 36.42 ± 4.66 | 57.47 ± 5.75 | 93.20 ± 4.42 | 53.95 ± 7.53 | 176.95 ± 6.69 | 106.12 ± 8.39 | 63.17 ± 4.86 |
| C57 BL/6 | 89.40 ± 4.80 | 43.30 ± 3.69 | 63.02 ± 6.57 | 100.73 ± 4.86 | 60.90 ± 6.05 | 201.50 ± 12.25 | 126.52 ± 6.89 | 77.38 ± 6.19 |
| C57 BL/10 | 87.89 ± 7.08 | 36.80 ± 6.48 | 60.36 ± 4.03 | 104.11 ± 6.44 | 58.37 ± 7.94 | 199.37 ± 10.13 | 97.50 ± 6.02 | 82.80 ± 3.24 |
| C57 BR | 82.93 ± 4.55 | 47.98 ± 7.34 | 62.72 ± 7.93 | 91.23 ± 6.52 | 53.52 ± 4.64 | 168.95 ± 16.19 | 104.88 ± 10.61 | 67.48 ± 11.70 |
| C58 | 87.13 ± 5.74 | 46.97 ± 10.37 | 59.69 ± 4.49 | 100.84 ± 6.89 | 60.01 ± 2.84 | 198.10 ± 8.43 | 103.83 ± 9.46 | 75.07 ± 6.90 |
| DBA/2 | 87.07 ± 6.75 | 48.70 ± 5.67 | 51.78 ± 11.96 | 106.58 ± 5.32 | 57.28 ± 11.98 | 181.37 ± 7.71 | 91.72 ± 4.76 | 68.25 ± 3.33 |
| 129 | 85.07 ± 4.17 | 55.80 ± 4.37 | 54.32 ± 6.56 | 106.25 ± 3.00 | 52.45 ± 4.25 | 198.68 ± 13.70 | 96.28 ± 6.93 | 98.57 ± 5.12 |
| AKR | 63.62 ± 7.90 | 48.18 ± 20.14 | 49.51 ± 4.74 | 84.69 ± 11.91 | 54.68 ± 11.06 | 173.96 ± 21.26 | 100.37 ± 7.20 | 91.40 ± 10.12 |
| DBA 1 | 77.27 ± 1.80 | 48.17 ± 6.75 | 59.22 ± 3.26 | 88.81 ± 4.63 | 48.95 ± 9.76 | 220.05 ± 10.40 | 140.92 ± 15.40 | 98.51 ± 8.92 |
| RIII | 74.75 ± 10.89 | 41.06 ± 12.70 | 65.44 ± 8.66 | 58.20 ± 7.00 | 25.91 ± 5.62 | 145.29 ± 21.10 | 125.07 ± 12.94 | 83.69 ± 22.53 |
Statistical analysis (repeated-measures two-way ANOVA) revealed a significant effect of strain (P = 0.0078), region (P < 0.000001), and strain-region interaction (P = 0.000003).