Table 1

Mean LC50 of NCI DTP database compounds examined

CompoundMean LC50Statistical Significance
Wild Type p53Mutant p53
μM
NSC-3029795.4  ± 1051-a 6.6  ± 105b Indistinguishable (p ≫ 0.05)
Curcumin6.1  ± 1051-a 6.8  ± 105b Indistinguishable (p≫ 0.05)
NSC-156236InactiveInactive
  • 1-a Results from 18 cell lines with wild-type p53.

  • 1-b Results from 41 to 42 cell lines with mutant/deleted p53.