Compound | Mean LC50 | Statistical Significance | |
---|---|---|---|
Wild Type p53 | Mutant p53 | ||
μM | |||
NSC-302979 | 5.4 ± 1051-a | 6.6 ± 105b | Indistinguishable (p ≫ 0.05) |
Curcumin | 6.1 ± 1051-a | 6.8 ± 105b | Indistinguishable (p≫ 0.05) |
NSC-156236 | Inactive | Inactive |
↵1-a Results from 18 cell lines with wild-type p53.
1-b Results from 41 to 42 cell lines with mutant/deleted p53.