Effects of vanilloid receptor agonists in guinea pig mesenteric arteries (MA) and main bronchi (MB)
| Mesenteric Arteries | Main Bronchi | EC50 ratio | |||||
|---|---|---|---|---|---|---|---|
| Agonist | n | Emax | pEC50 | n | Emax | pEC50 | (MB/MA) |
| Anandamide | 15 | 98 ± 1 | 6.1 ± 0.1 | 6 | >28 ± 6 | <5.4 ± 0.11-a | >4.4 |
| Capsaicin | 6 | 97 ± 1 | 8.1 ± 0.1 | 7 | 117 ± 7 | 8.0 ± 0.1 | 1.4 |
| Resiniferatoxin | 7 | 95 ± 2 | 10.5 ± 0.1 | 5 | 98 ± 6 | 9.3 ± 0.11-a | 16 |
| Olvanil | 6 | 95 ± 2 | 8.2 ± 0.1 | 9 | >60 ± 8 | <5.2 ± 0.11-a | >467 |