Affinities of adenosine receptor ligands determined by competition against 0.5 nM [125I]AB-MECA binding to MDDC membranes.
| Ligand | Ki | 95% Confidence Interval |
|---|---|---|
| nM | ||
| 2Cl-IB-MECA | 1.5 | 1.1–2.0 |
| IB-MECA | 1.1 | 0.9–1.5 |
| VUF5574 | 0.5 | 0.2–1.5 |
| MRS1220 | 1.0 | 0.5–1.7 |
| CGS21680 | 52 | 24–113 |
| DPCPX | 251 | 122–516 |
| ZM241385 | >10,000 | |
| SCH58261 | >10,000 | |
DPCPX, 8-cyclopentyl-1,3-dipropylxanthine.