Table 1

Amplitude of contractile responses to bethanechol in β 4−/− (n = 5) and wild-type (n = 20) mice

Dose1 μM3 μM10 μM3 μM1-a
β4−/− mice0.52  ± 0.100.70  ± 0.081.05  ± 0.040.75  ± 0.11
WT mice0.50  ± 0.120.69  ± 0.140.92  ± 0.160.69  ± 0.14

Amplitudes of responses (grams) are given as mean ± S.D. There was no difference between β 4−/− and WT mice in different doses (p > 0.05, t test).

    • ↵1-a Repeated administration of bethanechol at the end of the experiments.