Table 1

Details of the carbamazepine-hypersensitive patients

PatientAgeGenderTime to ReactionDetails of ReactionTime Since ReactionRechallenge
years days months
169Male21Widespread maculopapular eruption with tissue eosinophilia16No
265Female42Maculopapular eruption, fever, eosinophilia, abnormal liver function tests72No
365Female1 (rechallenge)Desquamating rash with fever on inadvertent rechallenge; history of rash on initial exposure<11-a Positive
427Female1Widespread maculopapular rash with mild fever and eosinophilia after one dose; history of allergy to multiple antibiotics and possible exposure to carbamazepine in the past with development of rash 2Previous exposure  likely
526Male21Widespread rash with fever; history of allergy to multiple drugs including lamotrigine and phenytoin24No
  • 1-a The time blood was taken after rechallenge with CBZ.