Evaluation of the interaction between cisplatin and gemcitabine in ovarian cancer cell lines by median drug effect analysis
| Cell Line | Average CI ± S.E. | |||
|---|---|---|---|---|
| Fa25 | Fa50 | Fa75 | Fa90 | |
| 2008 | 0.55 ± 0.03 | 0.61 ± 0.04 | 0.68 ± 0.04 | 0.77 ± 0.03 |
| C13*5.25 | 1.13 ± 0.06 | 0.88 ± 0.05 | 0.67 ± 0.05 | 0.55 ± 0.04 |
| A2780 | 0.45 ± 0.05 | 0.64 ± 0.08 | 0.68 ± 0.07 | 0.71 ± 0.07 |
| CP70 | 0.89 ± 0.05 | 0.84 ± 0.06 | 0.79 ± 0.04 | 0.72 ± 0.04 |
Values represent CIs (non-mutually exclusive case) calculated at the fraction affected (Fa) of 0.25, 0.5, 0.75, and 0.9 of the combination of cisplatin and gemcitabine and are means ± S.E. of at least three separate experiments.