Table 1

Putative LXREs in the PON-1 gene promoter

SequencesConsensus FitPosition
TGTACTtgagTGAACT 11/12−552; −537
TAGCCTggtgAGAACA 9/12−469; −454
AAAGCTtgacTGTCCT 9/12−331; −316

The DNA sequence was searched to find elements fitting the DR4/LXRE consensus T(G/A)A(C/A)C(T/C)nnnnT(G/A)A(C/A)C(T/C) (Lu et al., 2001). Three sequences were identified in the 1-kb promoter used in transfection experiments. Their fitting with the consensus sequence are indicated as well as their positions in the promoter sequence (the +1 position corresponds to the A of the start codon).