Table 1

Effect of FAP-12 on S1P receptors

	FAP-12 Alone		S1P + FAP-12
	FAP-12	Response	S1P	FAP-12	Response
	μM	% of vehicle	μM	μM	% of S1P
S1P₁	10	95 ± 5^1-a	0.3	10	97 ± 4^1-a
S1P₂	10	100 ± 0^1-b	0.3	1	99 ± 11^1-b
S1P₃	10	100 ± 0^1-b	1	1	104 ± 13^1-b
S1P₅	10	90 ± 5^1-a	0.3	10	101 ± 2^1-a

↵1-a Results were obtained using [³⁵S]GTP-γ -S binding assay.
↵1-b Results were obtained using intracellular Ca²⁺-monitoring.