Data represent mean ± S.E.M. for at least three separate determinations in which Ki values were measured by radioligand displacement assays (see Materials and Methods). Fenfluramine is known to induce VHD in humans. | |
---|---|
Drug | Ki (pKi) |
nM | |
Fenfluramine | 4134 (5.9 ± 0.2) |
Norfenfluramine | 15 (7.83 ± 0.06) |
Dihydroergotamine | 15.2 (7.82 ± 0.06) |
Pergolide | 14 (7.8 ± 0.1) |
(R,S)-MDMA | 500 (6.30 ± 0.08) |
(R,S)-MDA | 100 (6.8 ± 0.1) |