TABLE 3

Thermodynamic values for the binding of bupivacaine to Kv2.1 at +60 mV

Dissociation constants at different temperatures. Each value represents three to six measurements.
Kd
297 K 305 K Enthalpy ΔH Entropy ΔS
kJ / mol kJ / mol / K
220 ± 30 180 ± 20 18.9 20.8