Human 5-HT2C Receptors | Receptor Densitya | Ki for 5-HT Bindinga | GTPγ[35S] Binding | ||
---|---|---|---|---|---|
5-HT | +PNU-69176Eb | 5-HT Emax | +PNU-69176Eb | ||
pmol/mg protein | nM | fmol/mg of protein | % of 5-HT | ||
HEK293-A | 45±3 | 159±12 | 10±1 | 724±36 | 50±3 |
SH-EP-A | 12.4±2 | 168±7 | 19±1 | 437±39 | 23±3 |
NIH3T3 | 11.9±0.6 | 176±10 | 11±1 | 282±19 | 50±4 |
HEK293-B | 6.6±1 | 223±16 | 32±3 | 213±8 | 35±4 |