TPMT and HPRT activity (mean ± S.E.M.) in RBC and WBC from untreated Msh2+/+, Msh2+/−, and Msh2−/− mice
| Genotype | RBC | WBC | Murine Embryonic Fibroblasts | ||
|---|---|---|---|---|---|
| TPMT | TPMT | HPRT | TPMT | HPRT | |
| U/ml packed RBC | nmol / h / 109 cells | nmol / h / 106 cells | nmol / h / 109 cells | nmol / h / 106 cells | |
| Msh2−/− | 7.6 ± 3.1 | 10.4 ± 3.5 | 8.2 ± 0.9 | 6.1 ± 3.9 | 17.6 ± 0.8 |
| Msh2+/− | 6.8 ± 1.9 | 8.3 ± 3.2 | 5.2 ± 1.1 | N/A | N/A |
| Msh2+/+ | 7.4 ± 1.9 | 16.8 ± 3.0 | 8.2 ± 1.9 | 26.2 ± 5.3 | 16.2 ± 1.4 |