List of SNPs identified by genomic DNA sequencing from 12 Ethiopians phenotyped using caffeine and with high or low caffeine MR Numbering is from the translation site as recommended by the cytochromes P450 nomenclature committee. Smoking habit is designated as S and NS, referring to smokers and non-smokers respectively.
| -164 C>A | -730C>T | -740T>G | 30G>A (Silent) exon 2 | 1589G>T intron 3 | 1611 G>A intron 3 | 2159 A>G intron 4 | 2848 C>A intron 5 | 3614 T>C intron 6 | 5347 T>C (Silent) exon 7 | 6676C>G exon 7 Noncoding | Caffeine MR | Caffeine Log MR | Smoking Habit |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C/C | G/G | 20 | 1.3 | S | |||||||||
| C/A | A/G | C/C | 12 | 1.1 | S | ||||||||
| A/A | T/G | G/T | A/G | C/A | T/C | C/C | C/G | 21 | 1.3 | S | |||
| C/A | G/A | A/G | 1 | 0 | NS | ||||||||
| A/A | 3 | 0.5 | NS | ||||||||||
| C/C | G/G | 5 | 0.7 | NS | |||||||||
| C/A | A/G | C/C | 6 | 0.8 | NS | ||||||||
| A/A | C/T | T/G | A/G | T/C | T/C | C/G | 8 | 0.9 | NS | ||||
| C/A | A/G | T/C | 10 | 1.0 | NS | ||||||||
| A/A | A/G | T/C | 230 | 2.4 | S | ||||||||
| A/A | 218 | 2.3 | S | ||||||||||
| A/A | T/G | G/A | 11 | 1.0 | NS |