GAF motif-containing proteins
| Protein | Number of GAF Motifs | Functions | Organisms |
|---|---|---|---|
| Adenylyl cyclase | 1-2 | Signal transduction | Bacteria |
| Ethylene receptor | 1 | Ethylene metabolism | Plant (Tracheophyta), bacteria |
| Sensory histidine kinase | 1-2 | Signal transduction | Archea, bacteria, fungi, yeast |
| Two-component sensor histidine kinase | 1-2-3-4 | Signal transduction | Bacteria, viruses |
| Ser/Thr protein kinase | 1-2 | Signal transduction | Bacteria |
| Autolysin sensor kinase | 1 | Cell autolysis | Bacteria |
| LytS and LytR | 1 | Cell autolysis | Bacteria |
| cN phosphodiesterase | 1-2 | Signal transduction | Protobacteria, bacteria, trypanosomatids, sponges, insects, nematodes, mammals |
| Diguanylate cyclase/phosphodiesterase | 1-2 | Signal transduction | Bacteria |
| Methyl-accepting chemotaxis protein | 1-3-4 | Chemotaxis | Bacteria |
| Phosphoglucose isomerase | 1 | Glucose metabolism | Plant (Tracheophyta) |
| Phosphoenolpyruvate protein phosphotransferase | 1 | Glucose metabolism | Bacteria |
| Nitrate/nitrile sensor protein | 1 | Nitrogen fixation | Bacteria |
| Formate hydrogenlyase transcriptional activator | 2 | Gene regulation | Bacteria |
| NifA-specific transcriptional regulator | 1 | Gene regulation, nitrogen fixation | Bacteria, plasmodium |
| NtrC-specific transcriptional regulator | 1 | Gene regulation | Dictyostelium, bacteria |
| Sigma factor regulator of σ-B activity | 1-2 | Gene regulation | Bacteria |
| Transcriptional regulator AcoR | 1 | Gene regulation | Bacteria |
| Glycerol metabolism operon regulatory protein | 1 | Gene regulation | Bacteria |
| Bacterio-opsin activator | 1 | Phototransduction | Archea |
| Circadian protein kinase | 1 | Phototransduction | Archea |
| Phytochromes (A, B, C, D, E, F, N, O, P) | 1 | Phototransduction | Plant (Tracheophyta) |
| Photoreceptor | 1 | Phototransduction | Plant (Bryophyta) |
| Bacteriophytochrome | 1 | Phototransduction | Bacteria |
NifA, specific activator of Nif genes; NtrC, nitrogen-regulatory protein C.